Liquid NMR, Strasbourg, France

Liquid state NMR

NMR spectroscopy provides invaluable insights into the structural and dynamical features of biomolecular systems. We are taking advantage of NMR, combined with other structural biology methods, to investigate molecular properties that are important to achieve a given biological function.

Two spectrometers are installed in the lab: a 600 MHz and a 700 MHz with cryo-probes to achieve highest sensitivity.

600 MHz spectrometer: For experiments that need high sensitivity and resolution, the 600 MHz spectrometer with a QCI-F CryoProbe^TM achieves high sensitivity on ¹³C, ¹H,and ¹⁹F with ¹⁵N and ²H decoupling and Z gradients.

700 MHz spectrometer: For experiments that need extreme sensitivity and resolution, the 700 MHZ spectrometer with a selective proton and carbon CryoProbe^TM with nitrogen/carbon/deuterium decoupling and Z gradients.

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