The platform at the Biomolecular Interactions and Crystallography core facility (BIC) at CEITEC Instruct centre provides instruments and services leading to the biophysical characterization of (bio)molecules, the study of biomolecular interactions (determination of affinity, kinetic and thermodynamic parameters) and the sample quality control using analytical ultracentrifugation (AUC), isothermal titration calorimetry (ITC), surface plasmon resonance (SPR), bio-layer interferometry (BLI), microscale thermophoresis (MST), dynamic light scattering (DLS), differential scanning calorimetry (DSC), differential scanning fluorimetry (DSF), and analytical size-exclusion chromatography (SEC-MALS). The platform is available to the entire INSTRUCT-ERIC community every working day upon previous agreement.
More information can be found on the Biomolecular Interactions and Crystallography core facility webpage
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